Adjunct membership is for researchers employed by other institutions who collaborate with IDM Members to the extent that some of their own staff and/or postgraduate students may work within the IDM; for 3-year terms, which are renewable.
ANDRADE, Prof Bruno de Bezerril
Professor of Pathology, School of Medicine, Faculdade de Tecnologia e Ciências, Salvador, Brazil.
Dr Andrade is a clinical human immunologist specializing in biomarker discovery. His research is focused on the inflammatory responses in human chronic infections. Specifically, he is dedicated to identifying reliable host biomarkers that can predict susceptibility to infection and disease severity in tuberculosis (TB) and HIV. In addition, his research goals include identification of host molecules tightly linked to the pathogenesis of TB and HIV which can be targeted in host-directed therapies to reduce immunopathology. His research approaches combine epidemiological studies with cellular and humoral immunological assays.
BARRY III, Dr Clifton
PhD, Section Chief and Senior Investigator, Tuberculosis Research Section (TRS), National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health (NIH).
Areas of interest span the basic sciences of chemistry, biochemistry and microbiology, through to pharmacology and clinical medicine, in the areas of mycobacterial pathogenesis and TB drug discovery research.
BROWN, Prof Gordon
PhD, Associate Professor / Wellcome Senior Fellow
Areas of interest include pattern recognition receptors in innate immunity.
CORBETT, Dr Liz
Wellcome Trust Senior Fellow and a Clinical Epidemiologist with the London School of Hygiene and Tropical Medicine.
Areas of interest include control of TB in HIV prevalent populations from the public health perspective, with a focus on the epidemiology at primary care and community level, and intervention trials. Other ongoing research interests include mathematical modeling, management of smear-negative TB suspects, TB diagnostics, and in the epidemiology of adolescent long-term survivors of mother-to-child transmission of HIV infection.
GRAY, Assoc Prof Glenda
MBBCH, FCP (Paeds) SA. Executive Director Perinatal HIV Research Unit, Wits Health Consortium, University of Witwatersrand; Associate Professor, Department of Paediatrics, University of Witwatersrand, South Africa; HVTN Director of International Programmes; HVTN Co-Principal Investigator; Chair of the standing committee on Health, ASSAF.
Her Research Unit is involved with clinical research, epidemiology and operational research, and is a treatment site for HIV infected adults and children. Her research interests include HIV vaccine research, microbicide research and other biomedical and behavioural interventions, and she is an investigator in testing two HIV vaccine regimens in late stage clinical development. Her TB research includes examining new agents to prevent TB, TB prophylaxis and TB vaccine evaluation.
GROBUSCH, Prof Martin
Professor, Dr. Med. (M.D.), PhD, M.Sc. (Lond), DTM&H (Lond), FRCP (Lond). Specialist in Internal Medicine, Infectious Diseases, Tropical Medicine. Full Professor and Chair of Tropical Medicine and Travel Medicine and Head, Center of Tropical Medicine and Travel Medicine, Amsterdam Medical Centre, University of Amsterdam in the Netherlands.
He has been an author on over 150 manuscripts in the field of infectious diseases and has an extensive track record in infectious diseases research and practice covering clinical, laboratory and epidemiological aspects.
HARRISON, Prof Thomas
Professor of infectious diseases and medicine; Joint head of the Infection and Immunity Research Centre, St Georges, University of London.
Areas of interest include cryptococcal meningitis, opportunistic infection in HV tuberculosis, chemotherapy and lung resistance systemic fungal infection.
KAMPMANN, Dr Beate
FRCPCH DTM&H PhD; Wellcome Trust Intermediate Clinical Fellow, Senior Lecturer in Paediatric Infectious Diseases at Imperial College London, Honorary Consultant Paediatrician at St. Mary's Hospital, London. Paediatric tuberculosis, International Child Health.
Collaborations: IDM and Red Cross Children's Hospital, Cape Town, Staten Serum Institute, Denmark, Case Western Reserve University, USA.
LOPATA, Dr Andreas
PhD, Associate Professor, Comparative Genomics Centre, James Cook University, Townsville, Australia.
Research interests include allergic sensitivities to proteinacious food including immunomodulating components of parasites, food security and food labeling, and diagnostics of allergic and inflammatory diseases.
McSHANE, Prof Helen
The Jenner Institute, University of Oxford; Deputy Head of Department, Nuffield Department of Medicine; Professor of Vaccinology; Wellcome Trust Senior Clinical Research Fellow.
Research programme involves design of candidate vaccines against TB, testing in various preclinical models, and extensive clinical testing through first-in-man clinical trials to field efficacy trials. MVA85A, one of the vaccines she developed, was the first subunit vaccine to undergo field efficacy testing since BCG. Collaborates in clinical trials with, amongst others, SATVI and CIDRI (IDM). Current interests in immuno-monitoring in clinical trials, the development of human mycobacterial challenge models, and aerosol delivery of vaccines.
MOORE, A/Prof Penny
South African Research Chair in Viral Host Dynamics, Faculty of Health Sciences, University of Witwatersrand and National Institute for Communicable Diseases
Her current research focuses on HIV broadly neutralising antibodies and their interplay with the evolving virus. Recent studies published in PloS Pathogens, Nature and Nature Medicine have highlighted the role of viral escape in creating new epitopes and immunotypes, thereby driving the development of neutralisation breadth, with implications for HIV vaccine design.
NICOL, Prof Mark
School of Biomedical Sciences, Division of Infection and Immunity, University of Western Australia; Professor in Microbiology.
Research interest in tuberculosis and in developing and testing point of care diagnostics suitable for the developing world.
RYFFEL, Dr Bernhard
Director of Research, CNRS, and of the University Orléans, France.
Various areas of research focused on host defense, inflammation and immunology, and includes tuberculosis, malaria, asthma, colitis and humanized mice, with current research on inflammasome, IL-1pro-inflammatory mediator and Th17 cells, and recently, helminth induced lung inflammation.
SEOIGHE, Assoc Prof Cathal
PhD, previous Scientific Director of the University of Cape Town's National Bioinformatics Network Node; presently Stokes Professor of Bioinformatics, School of Mathematics, Statistics and Applied Mathematics, NUI Galway, Ireland.
Research interests: Modeling molecular biological data, including gene expression, alternative mRNA splicing, and viral evolution.
TABB, Prof David
PhD (Molecular Biotechnology); Division of Molecular Biology and Human Genetics, Stellenbosch University Faculty of Medicine and Health Science.
Experienced in mass spectrometry bioinformatics with 10 years in seeking colon cancer biomarkers through proteomic mass spectrometry. Presently an investigator in the South African Medical Research Council SHIP program, supporting tuberculosis researchers throughout South Africa with my bioinformatics and biostatistics experience. We seek to broaden the use of biological mass spectrometry, particularly in the Western Cape province.
TROMP, Prof Gerardus C.
PhD (Rutgers), FAHA. Professor in Bioinformatics at the South African Tuberculosis Bioinformatics Initiative (SATBBI), Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University.
Extensive experience in bioinformatics, gene expression data and epigenetic analyses. His mandate through his appointment is to provide lead bioinformatics support on various programmes and initiative, developing a sustainable group of bioinformaticians supporting TB and related research.
WILKINSON, Assoc Prof Katalin
Principal Laboratory Research Scientist Scientist at The Francis Crick Institute London; Honorary Senior Lecturer, Division of Infection and Immunity, University College London; Honorary Associate Professor, Department of Medicine, University of Cape Town.
Her research focuses on the immunology of HIV-associated tuberculosis, including the reconstitution of the immune response during antiretroviral treatment, the effect of treatment on potential biomarkers in HIV uninfected persons in order to identify correlates of protection and pathogenesis; the immunological characterisation of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS); the biosignature of active and latent tuberculosis, preventing tuberculosis infection in HIV infected people more effectively; and novel peptide based correlates of protection and diagnosis in tuberculosis.