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MEMBER LIST

  Full member Main areas of expertise
Stephan Barth

BARTH, Prof Stefan
Medical Biotechnology & Immunotherapy Group

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Medical biotechnology, antibody technologies, protein engineering, immunodiagnostics, bioassay development & integration, immunotherapeutics, targeted human cytolytic fusion proteins, SNAP-tag based fusion proteins, ex vivo / in vivo targeting
Linda-Gail Bekker

BEKKER, Prof Linda-Gail
Desmond Tutu HIV Centre

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Pathogenesis of tuberculosis and HIV infection
Jonathan Blackburn

BLACKBURN, Prof Jonathan
Applied Proteomics & Chemical Biology Group

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Enzymology; molecular biology; in vitro evolution; proteomics; protein arrays; protein-drug interactions; biomarker discovery & validation; biosensors
Frank Brombacher

BROMBACHER, Prof Frank
Cytokines and Disease Group, and International Centre for Genetic Engineering & Biotechnology (ICGEB)

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Immunology, tuberculosis, listeriosis, African trypanosomiasis, leishmaniasis, bilharzia, helminth infection, transgenic mouse models, transcriptomics
Wendy Burgers

BURGERS, Assoc Prof Wendy
Division of Medical Virology, UCT

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HIV pathogenesis, HIV-TB co-infection, HIV vaccine immunology
Kelly Chibale

CHIBALE, Prof Kelly
Drug Discovery Group

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Small molecule drug discovery underpinned by the integration of  chemistry, biology and pre-clinical pharmacology, including drug metabolism and pharmacokinetics (DMPK) as expressed in the processes of Absorption, Distribution Metabolism & Excretion (ADME).
Helen Cox

COX, Assoc Prof Helen
Division of Medical Microbiology, UCT

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Epidemiology of TB and drug-resistant TB, TB diagnostics and treatment

Clive Gray

GRAY, Prof Clive
Division of Immunology, UCT

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Immunopathogenesis of HIV, survival and differentiation of antigen-specific memory CD4 and CD8 T cells, vaccine-induced immunity
Janet Hapgood

HAPGOOD, Professor Janet
Department of Molecular and Cell Biology, Faculty of Science

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Intracellular molecular mechanisms of action of steroid receptors; the glucocorticoid receptor, in the broad context of reproduction, inflammation, contraception and infectious disease, in particular HIV-1.

Mark Hatherill

HATHERILL, Prof Mark
South African Tuberculosis Vaccine Initiative (SATVI)

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Paediatric TB vaccine trials; diagnostic endpoints for childhood TB
Greg Hussey

HUSSEY, Prof Greg
Vaccines for Africa (VACFA)

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Vaccinology, clinical trials, tuberculosis, paediatric infectious diseases
Muazzam Jacobs

JACOBS, Prof Muazzam
Experimental Tuberculosis and Immunology Research Group

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Immunology of infectious disease, tumor necrosis factor, tuberculosis, small animal models, evaluation of anti-tuberculosis drug leads and drug delivery systems
Arieh Katz

KATZ, Prof Arieh
UCT/MRC Research Group for Receptor Biology

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G protein-coupled receptors , GnRH, kisspeptin, cervical cancer, Kaposi sarcoma
Susan Kidson

KIDSON, Prof Susan
Cell and Developmental Biology Research Group

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Molecular basis of eye development; models for inherited and acquired forms of glaucoma: skin pigmentation; embryonic stem cells; skin stem cells
Darren Martin

MARTIN, Assoc Prof Darren
Computational Biology Group

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Bioinformatics, virus evolution, genetic recombination
Graeme Meintjes

MEINTJES, Prof Graeme
Clinical Infectious Diseases Research Initiative (CIDRI)

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HIV-associated tuberculosis; tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS); cryptococcal meningitis
Bob Millar

MILLAR, Prof Robert
MRC/UCT Research Group for Receptor Biology

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Peptide regulators of reproductive hormones
Valerie Mizrahi

MIZRAHI, Prof Valerie
MRC/NHLS/UCT Molecular Mycobacteriology Research Unit

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Mycobacterial physiology and metabolism of particular relevance to TB drug resistance and drug discovery, including DNA repair and replication, central carbon metabolism, co-factor biosynthesis and function
Nicola Mulder

MULDER, Prof Nicola
Computational Biology Group

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Bioinformatics of infectious diseases from the perspectives of the host and the pathogen's biological systems
Mark Nicol

NICOL, Prof Mark
Division of Medical Microbiology, UCT

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Novel diagnostics for tuberculosis, strain biology of tuberculosis
Jo-Ann Passmore

PASSMORE, Assoc Prof Jo-Ann
Mucosal Immunology Laboratory

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HIV/HPV Mucosal Immunology; genital tract, innate immunity, cytokine biomarkers, genital tract immune activation
Raj Ramesar

RAMESAR, Prof Rajkumar
MRC Human Genetics Research Unit

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Genetic predisposition to cancer; eye or neuropsychiatric diseases
Ed Rybicki

RYBICKI, Prof Ed
URC Biopharming Research Unit

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Vaccine and viral biotechnology - novel human papillomavirus and rotavirus and human pandemic and avian influenza virus vaccine candidates made in plants via transient expression; investigation of the potential of plants to make Rift Valley and Crimean-Congo haemorrhagic fever virus and bluetongue virus vaccines; diversity studies and vaccine development for beak and feather disease virus of parrots; investigations of the diversity and molecular biology of maize streak virus host-virus interactions.
Tom Scriba

SCRIBA, Assoc Prof Tom
South African Tuberculosis Vaccine Initiative (SATVI)

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Clinical immunology, Tuberculosis and mycobacterial infection, novel TB vaccines
Trevor Sewell

SEWELL, Prof Trevor
Structural Biology Group

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Large biological structures, inter-molecular interactions, chaperoning nitrilases and chromatin
Ed Sturrock

STURROCK, Prof Ed
Zinc Metalloprotease Research Group

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Protein biochemistry, protease inhibitor design, enzyme structure-function relationships, ectodomain shedding of angiotensin-converting enzyme
Jack van Honk

VAN HONK, Prof Jack
Social and Clinical Neuroscience

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Social and Affective Neuroscience (Human Neuroscience), psychobiology of human social-emotional behavior, psychopathologies of fear and aggression
Katalin Wilkinson

WILKINSON, Assoc Prof Katalin
Clinical Infectious Diseases Research Initiative (CIDRI)

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Immunology of HIV-associated tuberculosis
Robert Wilkinson

WILKINSON, Hon Prof Robert John
Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa)

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Tuberculosis and the effect of HIV infection on this disease. Investigations include the role of Interferon gamma release assays in the diagnosis of HIV- associated tuberculosis; the immune effects of preventive therapies against TB (HAART, IPT and vitamin D); the HIV-TB immune reconstitution inflammatory syndrome; clinical consequences of strain variation within M. tuberculosis
Anna-Lise Williamson

WILLIAMSON, Prof Anna-Lise
HIV Vaccine Development Group and Human Papillomavirus Research Group

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HIV, papillomavirus, poxviruses, vaccine development
Carolyn Williamson

WILLIAMSON, Prof Carolyn
HIV Diversity and Pathogenesis Research Group

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HIV diversity and pathogenesis; HIV-1 vaccine development, microbicides
Ambroise Wonkam

WONKAM, Prof Ambroise
GENEMAP (Genetic Medicine of African Populations)

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Genetic Medicine, Sickle Cell Disease, Hearing Impairment, Medical Ethics, Genetic Education
Robin Wood

WOOD, Prof Robin
Desmond Tutu HIV Centre

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Pathogenesis of tuberculosis and HIV infection
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  Associate member Main areas of expertise
Anna Coussens

COUSSENS, Dr Anna
Clinical Infectious Diseases Research Initiative (CIDRI)

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Immunopathogenesis of TB-HIV, biomarkers of infection, host-directed therapies, 3D models of infection, live-cell imaging

Collet Dandara DANDARA, Prof Collet

Pharmacogenomics, Drug Metabolism and Cancer Research Group

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Pharmacogenomics, drug metabolism, human genetic variation, genetic susceptibility

Reto Guler GULER, Dr Reto

International Centre for Genetic Engineering & Biotechnology (ICGEB), Cape Town component, and Division of Immunology, UCT

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Immunology, infectious diseases, tuberculosis, listeriosis, leishmaniasis, identification of host-directed drug targets, transcriptomics, non-coding RNA, microRNA, lncRNA

William Horsnell

HORSNELL, Assoc Prof William
Parasite Immune Regulation Laboratory
Division of Immunology, UCT

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Immunology, infectious diseases, parasitology, helminth infections, co-infection, acetylcholine signalling in the immune system
Claire Hoving

HOVING, Dr J Claire
Fungal Immunology Group
Division of Immunology, UCT

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Basic immunology, host immune responses to disease; HIV-related fungal infections such as Pneumocystis jirovecii; Mycobacterium tuberculosis.
Heather Jaspan

JASPAN, Dr Heather
Division of Immunology, UCT

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HIV/AIDS, paediatrics, vaccines, adolescent and neonatal HIV prevention
Virna Leaner

LEANER, Prof Virna
Transcriptional Regulation and Cancer Biology

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Cancer biology, molecular biology, gene expression patterns, transcriptional regulation, nuclear transport proteins
Jackson Marakalala

MARAKALALA, Dr Mohlopheni Jackson
TB Immunopathogenesis Group

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Host factors driving immunopathogenesis during TB progression using molecular histology techniques; mycobacterial genes for host survival
Musa Mhlanga

MHLANGA, Dr Musa
Biomedical Translational Research Initiative (BTRI)

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Quantitative imaging to "eavesdrop" on cellular events at the single molecule scale including the development of super resolution microscopy tools (e.g. QuickPALM) and the use of such tools to study higher order signalosomes. Focus on understanding the fundamental roles of genome architecture and RNA in spatial control of gene expression.
Keren Middelkoop

MIDDELKOOP, Dr Keren
Desmond Tutu HIV Centre

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Pathogenesis of tuberculosis and HIV infection
Catherine Orrell

ORRELL, Assoc Prof Catherine
Desmond Tutu HIV Centre

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HIV: adherence, retention and resistance
Joseph Valentino Raimondo RAIMONDO, Dr Joseph Valentino

Neurophysiology Research Group

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Neurophysiology, epilepsy, synaptic transmission, plasticity, neurocysticercosis, patch-clamp electrophysiology, optical imaging, neuronal biophysics

Catherine Riou RIOU, Dr Catherine

Division of Medical Virology, UCT

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T cell immunology, Infectious Diseases, HIV/TB co-infection
Georgia Schafer

SCHÄFER, Dr Georgia
Division of Medical Biochemistry, UCT

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Oncogenic viruses, Host-pathogen interactions, Cancer Biology, Transcriptional Regulation
Digby Warner

SMITH, Dr Katherine
Marie Sklodowska-Curie Global Fellow

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Immunology, infectious diseases, helminth infections, colorectal cancer, immune-regulation
Digby Warner

WARNER, Assoc Prof Digby
MRC/NHLS/UCT Molecular Mycobacteriology Research Unit

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Mycobacterial physiology, in particular the mechanisms and regulation of DNA repair and replication in Mycobacterium tuberculosis and their role in the emergence of drug resistance, the physiological consequences of drug resistance, and the role of vitamin B12 and related co-factors in mycobacterial pathogenesis
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  Affiliate members Main areas of expertise
 

BARNES, Prof Karen
Division of Clinical Pharmacology, UCT

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Comprehensive evaluation of malaria treatment policy changes in southern Africa, to improving anti-malarial dosing regimens for vulnerable populations (including young children, pregnant women and those with prevalent co-morbidities, including malnutrition and HIV) and more recently leading Phase 1 clinical trials on novel antimalarial compounds
 

BOULLE, Prof Andrew
Centre of Infectious Disease Epidemiology and Research, UCT

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HIV cohort epidemiology, HIV and TB service monitoring and evaluation, infectious disease modelling, and cost modelling.
 

COETZEE, Dr David
Centre of Infectious Disease Epidemiology and Research, UCT

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Public health specialist including operational experience in primary care and infectious disease service delivery
 

DHEDA, Assoc Prof Keertan
Lung Infection and Immunity Unit, UCT

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Study of pulmonary regulatory immunological pathways in relation to infection, rapid and field-friendly diagnosis of tuberculosis, and drug-resistant tuberculosis
 

ELEY, Assoc Prof Brian S
Paediatric Infectious Diseases, Red Cross Children's Hospital

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HAART in children; immune reconstitution in children; TB-HIV co-infection; MRSA infection; primary immunodeficiency diseases
 

MAARTENS, Prof Gary
Division of Clinical Pharmacology, UCT

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HIV-associated tuberculosis, antiretroviral therapy (adherence, pharmacokinetics, pharmacoeconomics, and tolerability)
 

MAYOSI, Prof Bongani M
Department of Medicine, UCT

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Genetics of heart disease, management of tuberculous pericarditis, and prevention of rheumatic heart disease
 

McILLERON, Prof Helen
Division of Clinical Pharmacology, UCT

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Pharmacometrics research, specializing in nonlinear mixed effects analysis
 

MYER, Prof Landon
Centre for Infectious Disease Epidemiology and Research, UCT

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Epidemiology of HIV, other sexually transmitted infections & tuberculosis; evaluation of HIV treatment and prevention interventions; reproductive health of HIV-infected individuals; socioeconomic determinants of population health
 

NAIDOO, Prof Kevin
Department of Chemistry, UCT

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Computational scientist with expertise in the development of Parallel and Hybrid model computer codes for application to chemical, life and biomedical sciences. Research is balanced between development of life science software and its application to biomedical projects where more recently the biomedical application has been cancer
 

NTSEKHE, Prof Mpiko
Department of Medicine, UCT

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Investigation of the Management of Pericarditis (IMPI), Inflammatory determinants of disease severity and treatment outcome in TB patients, Left Cardiac Sympathetic Denervation for Cardiomyopathy Pilot Study, HIV Associated Myocardial Fibrosis Study
 

PARKER, Prof M Iqbal
MRC/UCT Oesophageal Cancer Research Group, and International Centre for Genetic Engineering & Biotechnology (ICGEB)

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Oesophageal cancer, tumour metastasis, drug development
 

SLIWA-HAHNLE, Dr Karen
Hatter Institute for Cardiology Research, UCT

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Various topics related to cardiovascular medicine
 

STEIN, Prof Dan
Department of Psychiatry and Mental Health, UCT

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Psychiatry; trauma and resilience, substance use and NeuroHIV
 

ZAR, Prof Heather
Paediatric Pulmonology, Red Cross Children's Hospital

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Child lung health including HIV-associated lung disease, childhood pneumonia and childhood TB
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  Adjunct members Main areas of expertise
 

ANDRADE, Prof Bruno de Bezerril
School of Medicine, Faculdade de Tecnologia e Ciências, Salvador, Brazil

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Clinical human immunologist specializing in biomarker discovery; inflammatory responses in human chronic infections
 

BARRY III, Dr Clifton
National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health (NIH)

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Basic sciences of chemistry, biochemistry and microbiology, through to pharmacology and clinical medicine, in the areas of mycobacterial pathogenesis and TB drug discovery research

 

BROWN, Prof Gordon
University of Aberdeen, UK

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Pattern recognition receptors in innate immunity
 

CORBETT, Dr Liz
London School of Hygiene and Tropical Medicine, UK

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Control of TB in HIV prevalent populations from the public health perspective, with a focus on the epidemiology at primary care and community level, and intervention trials; mathematical modeling, management of smear-negative TB suspects, TB diagnostics, and in the epidemiology of adolescent long-term survivors of mother-to-child transmission of HIV infection
 

GRAY, Assoc Prof Glenda
Department of Paediatrics, University of Witwatersrand, South Africa

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HIV vaccine research, microbicide research and other biomedical and behavioural interventions, and she is an investigator in testing two HIV vaccine regimens in late stage clinical development. Her TB research includes examining new agents to prevent TB, TB prophylaxis and TB vaccine evaluation.
 

GROBUSCH, Prof Martin
Amsterdam Medical Centre, University of Amsterdam, Netherlands

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Infectious diseases research and practice covering clinical, laboratory and epidemiological aspects.
 

HARRISON, Prof Thomas
St Georges, University of London, UK

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Cryptococcal meningitis, opportunistic infection in HV tuberculosis, chemotherapy and lung resistance systemic fungal infection
 

KAMPMANN, Dr Beate
Imperial College London, UK

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Paediatric tuberculosis, International Child Health
 

LOPATA, Dr Andreas
James Cook University, Townsville, Australia

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Allergic sensitivities to proteinacious food including immunomodulating components of parasites, food security and food labeling; diagnostics of allergic and inflammatory diseases
 

McSHANE, Prof Helen
The Jenner Institute, University of Oxford, UK

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Consultant HIV physician; research into mycobacterial immunity and the development of new vaccines for tuberculosis
 

RYFFEL, Dr Bernhard
University Orléans, France

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Host defense, inflammation and immunology, and includes tuberculosis, malaria, asthma, colitis and humanized mice, with current research on inflammasome, IL-1pro-inflammatory mediator and Th17 cells, and recently, helminth induced lung inflammation
 

SEOIGHE, Assoc Prof Cathal
NUI Galway, Ireland

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Modeling molecular biological data, including gene expression, alternative mRNA splicing, and viral evolution
 

TABB, Prof David
University of Stellenbosch

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Mass spectrometry bioinformatics and biostatistics, supporting tuberculosis research
 

TROMP, Prof Gerardus C.
Division of Molecular Biology and Human Genetics, University of Stellenbosch

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Bioinformatics, gene expression data and epigenetic analyses
 

WILKINSON, Assoc Prof Katalin
The Francis Crick Institute, Mill Hill Laboratory, London, UK

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Immunology of HIV-associated tuberculosis

 

 

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